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CDCB2018 Programme
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CDCB2018 & ASCB Local Meeting PROGRAMME

Sunday, October 21, 2018
13:00 - 17:00 Registration
14:00 - 14:15 Grand Opening (Chair: Xuebiao Yao)
Dr. Xinhe Bao, President, USTC
Dr. Erika Shugart, CEO-ASCB
Dr. Ye-Guang Chen, President-CSCB

Keynote Lecture I (Chair: Yunyu Shi) 
14:15 - 15:15 Jiayang Li, Institute for Genetics & Developmental Biology, Beijing, CN
15:15 - 15:30 Group Photo

Session 1 CELL FATE DECISION & SIGNALING (Chair: Ye-Guang Chen)
15:30 - 16:00 Yi Zeng, Shanghai Institutes for Biological Sciences, Shanghai, CN
Wnt Signaling in Regulating Mammary Stem Cells and Breast Cancer
16:00 - 16:30 Chengqi Yi, Peking University, Beijing, CN
Chemical-assisted Sequencing of Epigenetic Nucleic Acid Modifications
16:30 - 17:00 Xiao-Fan Wang, Duke University, Durham, USA
New Insights into the Cellular Senescence and Cancer
17:00 - 17:30 Bin Zhou, Shanghai Institute of Biochemistry & Cell Biology, Shanghai, CN
Understanding Cell Fate Plasticity by Genetic Lineage Tracing
17:30 - 18:00 Yibin Kang, Princeton University, Princeton, USA
Epithelial-mesenchymal Plasticity and Dynamics in Breast Cancer Metastasis

Monday, October 22, 2018
Keynote Lecture II (Chair: Lin Li) 
08:30 - 09:30 Tony Hunter, Salk Institute, USA
New Signal Transduction Targets in Cancer Therapy
09:30 - 09:45 Group Photo

Session 2 MEMBRANE TRAFFICKING & MOLECULAR BIOPHYSICS (Chair: Arshad Desai)
09:45 - 10:15 Josep Rizo, University of Texas Southwest Medical Center, Dallas, USA
Molecular Mechanisms Underlying Neurotransmitter Release and Exquisite regulation
10:15 - 10:45 Shinji Asano, Ritsumeikan University, Kyoto, JP
Physiological Regulation of Membrane Transport by Actin-binding Proteins
10:45 - 11:15 Guoqiang Bi, University of Science & Technology of China, Hefei, CN
Ultra-structural Analyses of Neuronal Synapse using Cryo-electron Tomography and Correlative Microscopy 
11:15 - 11:45 Ying Lai, Stanford University, Palo Alto, USA
Munc13 and Munc18 Cooperate to Properly Assemble SNAREs for Fast Neurotransmitter Release
11:45 - 12:15 Changlin Tian, Hefei National Science Center for Physical Sciences, Hefei, CN
Conformation Exchange-based Ionic Selectivity for NaK Channel Revealed by NMR Studies

Session 3 BIOMOLECULAR CONDENSATES AND DYNAMICS (Chair: Josep Rizo)
13:30 - 14:00 Todd Stukenberg, University of Virginia, Charlottesville, USA
Phase Separation of the Inner Centromere Underlies Mitotic Signaling and Genomic Stability 
14:00 - 14:30 Shengqi Xiang, UMC Utrecht, Netherlands
Structural Studies of Nucleosomes and Human Cytoskeleton Proteins: the Power of High-sensitivity/Resolution Solid-state NMR Methods  
14:30 - 15:00 Pilong Li, Tsinghua University, Beijing, CN
Phase Transition in Gene Expression Activation and Repression
15:00 - 15:30 Jianfeng Chen, Shanghai Institutes for Biological Sciences, Shanghai, CN 
Integrin α4β7 Switches Its ligand Specificity via Distinct Conformer-specific Activation 

Keynote Lecture III (Chair: Xiao-Fan Wang) 
15:45 - 16:45 Bin Han, Institute for Plant Physiology, Shanghai, CN
Unlocking Genetic Diversity of Oryza Geomes Insights into Genomics of Rice Complex Traits and Breeding

Session 4 CELLULAR PLASTICITY & REGULATION (Chair: Jason Mills)
16:45 - 17:15 Celia Garcia, University of S?o Paulo, S?o Paulo, Brazil
PfSR25 in Anti-malarial Action and Stress Survival 
17:15 - 17:45 Yih-Cherng Liou, National University of Singapore, Singapore, SG
Microtubule-associated Proteins and Their Essential Roles on Chromosome Congression
17:45 - 18:15 Atsu Kuwahara, Ritsumeikan University, Kyoto, JP
Taste Sensing in the Colon
18:15 - 18:45 Yun Zhao, Shanghai Institute of Biochemistry & Cell Biology, Shanghai, CN
Ptc Functions as a Membrane Sponge of PKAc to Regulate Smo in Hh Signaling




Tuesday, October 23, 2018
Session 5 PROTEIN MACHINERY & MITOTIC REGULATION (Chair: Todd Stukenberg)
08:30 - 09:00 Arshad Desai, Ludwig Institute for Cancer Research, San Diego, USA
A New Mitotic Entry Function for a Core Spindle Checkpoint Complex 
09:00 - 09:30 Iain Cheeseman, MIT/Whitehead, Cambridge, USA 
Quiescent Cells Actively Replenish CENP-A Nucleosomes to Maintain Centromere Identity and Proliferative Potential 
09:30 - 10:00 Jianye Zang, University of Science & Technology of China, Hefei, CN
Structure Basis for the Recognition of  CENP-A Nucleosome by Inner Kinetochore Protein CENP-N
10:00 - 10:30 Geert Kops, KNAW, UMC Utrecht, Netherlands 
Make no Mistake: Chromosomal Instability and Karyotype Heterogeneity in Cancer

Session 6 EPIGENETICS & CELL FATE CONTROL (Chair: Iain Cheeseman)
10:45 - 11:15 Chengbin Xiang, Hefei National Science Center for Physical Sciences, Hefei, CN
HOMEOBOX PROTEIN 52 Mediates the Crosstalk between Ethylene and Auxin Signaling
11:15 - 11:45 Yong Ding, University of Science & Technology of China, Hefei, CN
A Plant-specific H2A Phosphorylation Modulates Flowering Time and Hypocotyl Elongation
11:45 - 12:15 Hong Zhang, Institute for Biophysics, Beijing, CN
Phase Separation and Transition Control Autophagic Degradation of PGL Granules

Session 7 CHEMICAL BIOLOGY OF CELL FATE DECISION (Chair: Yunyu Shi)
13:30 - 14:00 Peng Chen, Peking University, Beijing, CN
Bioorthogonal Cleavage Reactions in Living Systems
14:00 - 14:30 Chao Wang, University of Science & Technology of China, Hefei, CN
Serendipity with Ankyrin Scaffold Proteins: Potent and Specific Atg8-targeting Autophagy Inhibitory Peptides from Giant Ankyins
14:30
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