CDCB2018 & ASCB Local Meeting PROGRAMME

Sunday, October 21, 2018

13:00 - 17:00 Registration

14:00 - 14:15 Grand Opening (Chair: Xuebiao Yao)

Dr. Xinhe Bao, President, USTC

Dr. Erika Shugart, CEO-ASCB

Dr. Ye-Guang Chen, President-CSCB

Keynote Lecture I (Chair: Yunyu Shi) 

14:15 - 15:15 Jiayang Li, Institute for Genetics & Developmental Biology, Beijing, CN

15:15 - 15:30 Group Photo

Session 1 CELL FATE DECISION & SIGNALING (Chair: Ye-Guang Chen)

15:30 - 16:00 Yi Zeng, Shanghai Institutes for Biological Sciences, Shanghai, CN

Wnt Signaling in Regulating Mammary Stem Cells and Breast Cancer

16:00 - 16:30 Chengqi Yi, Peking University, Beijing, CN

Chemical-assisted Sequencing of Epigenetic Nucleic Acid Modifications

16:30 - 17:00 Xiao-Fan Wang, Duke University, Durham, USA

New Insights into the Cellular Senescence and Cancer

17:00 - 17:30 Bin Zhou, Shanghai Institute of Biochemistry & Cell Biology, Shanghai, CN

Understanding Cell Fate Plasticity by Genetic Lineage Tracing

17:30 - 18:00 Yibin Kang, Princeton University, Princeton, USA

Epithelial-mesenchymal Plasticity and Dynamics in Breast Cancer Metastasis

Monday, October 22, 2018

Keynote Lecture II (Chair: Lin Li) 

08:30 - 09:30 Tony Hunter, Salk Institute, USA

New Signal Transduction Targets in Cancer Therapy

09:30 - 09:45 Group Photo

Session 2 MEMBRANE TRAFFICKING & MOLECULAR BIOPHYSICS (Chair: Arshad Desai)

09:45 - 10:15 Josep Rizo, University of Texas Southwest Medical Center, Dallas, USA

Molecular Mechanisms Underlying Neurotransmitter Release and Exquisite regulation

10:15 - 10:45 Shinji Asano, Ritsumeikan University, Kyoto, JP

Physiological Regulation of Membrane Transport by Actin-binding Proteins

10:45 - 11:15 Guoqiang Bi, University of Science & Technology of China, Hefei, CN

Ultra-structural Analyses of Neuronal Synapse using Cryo-electron Tomography and Correlative Microscopy 

11:15 - 11:45 Ying Lai, Stanford University, Palo Alto, USA

Munc13 and Munc18 Cooperate to Properly Assemble SNAREs for Fast Neurotransmitter Release

11:45 - 12:15 Changlin Tian, Hefei National Science Center for Physical Sciences, Hefei, CN

Conformation Exchange-based Ionic Selectivity for NaK Channel Revealed by NMR Studies

Session 3 BIOMOLECULAR CONDENSATES AND DYNAMICS (Chair: Josep Rizo)

13:30 - 14:00 Todd Stukenberg, University of Virginia, Charlottesville, USA

Phase Separation of the Inner Centromere Underlies Mitotic Signaling and Genomic Stability 

14:00 - 14:30 Shengqi Xiang, UMC Utrecht, Netherlands

Structural Studies of Nucleosomes and Human Cytoskeleton Proteins: the Power of High-sensitivity/Resolution Solid-state NMR Methods  

14:30 - 15:00 Pilong Li, Tsinghua University, Beijing, CN

Phase Transition in Gene Expression Activation and Repression

15:00 - 15:30 Jianfeng Chen, Shanghai Institutes for Biological Sciences, Shanghai, CN 

Integrin α4β7 Switches Its ligand Specificity via Distinct Conformer-specific Activation 

Keynote Lecture III (Chair: Xiao-Fan Wang) 

15:45 - 16:45 Bin Han, Institute for Plant Physiology, Shanghai, CN

Unlocking Genetic Diversity of Oryza Geomes Insights into Genomics of Rice Complex Traits and Breeding

Session 4 CELLULAR PLASTICITY & REGULATION (Chair: Jason Mills)

16:45 - 17:15 Celia Garcia, University of S?o Paulo, S?o Paulo, Brazil

PfSR25 in Anti-malarial Action and Stress Survival 

17:15 - 17:45 Yih-Cherng Liou, National University of Singapore, Singapore, SG

Microtubule-associated Proteins and Their Essential Roles on Chromosome Congression

17:45 - 18:15 Atsu Kuwahara, Ritsumeikan University, Kyoto, JP

Taste Sensing in the Colon

18:15 - 18:45 Yun Zhao, Shanghai Institute of Biochemistry & Cell Biology, Shanghai, CN

Ptc Functions as a Membrane Sponge of PKAc to Regulate Smo in Hh Signaling

Tuesday, October 23, 2018

Session 5 PROTEIN MACHINERY & MITOTIC REGULATION (Chair: Todd Stukenberg)

08:30 - 09:00 Arshad Desai, Ludwig Institute for Cancer Research, San Diego, USA

A New Mitotic Entry Function for a Core Spindle Checkpoint Complex 

09:00 - 09:30 Iain Cheeseman, MIT/Whitehead, Cambridge, USA 

Quiescent Cells Actively Replenish CENP-A Nucleosomes to Maintain Centromere Identity and Proliferative Potential 

09:30 - 10:00 Jianye Zang, University of Science & Technology of China, Hefei, CN

Structure Basis for the Recognition of  CENP-A Nucleosome by Inner Kinetochore Protein CENP-N

10:00 - 10:30 Geert Kops, KNAW, UMC Utrecht, Netherlands 

Make no Mistake: Chromosomal Instability and Karyotype Heterogeneity in Cancer

Session 6 EPIGENETICS & CELL FATE CONTROL (Chair: Iain Cheeseman)

10:45 - 11:15 Chengbin Xiang, Hefei National Science Center for Physical Sciences, Hefei, CN

HOMEOBOX PROTEIN 52 Mediates the Crosstalk between Ethylene and Auxin Signaling

11:15 - 11:45 Yong Ding, University of Science & Technology of China, Hefei, CN

A Plant-specific H2A Phosphorylation Modulates Flowering Time and Hypocotyl Elongation

11:45 - 12:15 Hong Zhang, Institute for Biophysics, Beijing, CN

Phase Separation and Transition Control Autophagic Degradation of PGL Granules

Session 7 CHEMICAL BIOLOGY OF CELL FATE DECISION (Chair: Yunyu Shi)

13:30 - 14:00 Peng Chen, Peking University, Beijing, CN

Bioorthogonal Cleavage Reactions in Living Systems

14:00 - 14:30 Chao Wang, University of Science & Technology of China, Hefei, CN

Serendipity with Ankyrin Scaffold Proteins: Potent and Specific Atg8-targeting Autophagy Inhibitory Peptides from Giant Ankyins

14:30